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Home >> Plant Biotechnology and Genomics >> Genetically Modified-GM Crops and Floricultural Plants >> Mechanism of Action of Different Herbicides and Basis of Achieving Resistance them in Transgenic Plants

Mechanisms of action of different herbicides and basis of achieving resistance against them transgenic plants

Active principle of herbicide

Inhibited pathway

Target product

Use

Basis of resistance

I. Amino acid biosynthesis inhibitors

I. Glyphosate
   (Roundup)

Aromatic amino acid biosynthesis

EPSPS

Broad spectrum

Overexpression of EPSPS gene;
bacterial aroA gene

2. Sulphonylurea and
    Imidazolinones

Branched chain amino acids

ALS

Selected crops

Mutant ALS gene

3. Phosphinothricin
    (Basta)

Glutamine biosynthesis

GS

Broad spectrum

Gene amplification, bar gene : detoxification

II. Photosynthesis
  inhibitors

 

4. Atrazine
   (Lasso)

Photosystem II

QB (32kDa protein)

Selected crops

Mutant PsbA gene. GST gene:
detoxification

5. Bromoxynil
    (Buctril)

Photosynthesis

Selected crops

bxn gene:
detoxification


 

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