Gene for Virus Coat or Capsid Protein CP from Positive Strand RNA Viruses, Tobacco Mosaic Virus, RNA Virus, Coat Protein

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Home >> Plant Biotechnology and Genomics >> Genetically Modified-GM Crops and Floricultural Plants >> Gene for Virus Coat or Capside Protein CP from Positive Strand RNA Viruses

Gene for virus coat or capsid protein (CP) from positive strand RNA viruses

Coat protein gene from tobacco mosaic virus (TMV), classified as a positive strand RNA virus, has been transferred to tobacco, and in the transgenic plant, expression of coat protein (CP) was observed. Further, when inoculated with TMV, the infection in the transgenic plants was very low and delayed relative to control plants that were not transformed.

This provides a new approach for producing virus resistant plants complementing the efforts of classical plant breeding in producing disease resistant crop varieties.

However, in such transgenic plants, coat protein gene should be constitutively expressed and may thus have effects on the Nutritional value of plants approach has been applied to a range of crops (tomato, alfalfa, tobacco, potato, melons, rice) for developing resistance against a broad spectrum of positive RNA strand plant viruses (e.g. alfalfa mosaic virus, potato virus X = PYX, potato virus Y = PVY and potato leaf roll virus).

Potatoes have been produced which have coat protein genes and are tolerant to both PYX and PVY. DNA coding for a component of TMV replicase enzyme, was also transferred to tobacco plants, conferring resistance to TMV.

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