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  Home >> Molecular Biology Dictionary >> Hybrid selection - Hypoplastic

Hybrid selection
The process of choosing individuals possessing desired characteristics from among a hybrid population.

Hybrid vigour; heterosis
The extent to which the performance of a hybrid in one or more traits is better than the average performance of the two parental populations.

Hybridization
1. Interbreeding of species, races, varieties and so on, among plants or animals; a process of forming a hybrid by cross pollination of plants or by mating animals of different types.
2. The production of offspring of genetically different parents, normally from sexual reproduction, but also asexually by the fusion of protoplasts or by transformation.
3.The pairing of two polynucleotide strands, often from different sources, by hydrogen bonding between complementary nuc1eotides. See northern hybridization; Southern hybridization

4. The reaction by which the pairing of complementary strands of nucleic acid occurs. DNA is usually double-stranded, and when the strands are separated they will rehybridize under the appropriate conditions. Hybrids can form between DNA-DNA, DNA-RNA or RNA-RNA. They can form between a short strand and a long strand containing a region complementary to the short one. Imperfect hybrids can also form, but the more imperfect they are, the less stable they will be (and the less likely to form). To "anneal" two strands is the same as to "hybridize" them.

Hypervariable region

The parts of both the heavy and light chains of an antibody molecule that enable it to bind to a specific site on an antigen.

Hypervariable segment
A region of a protein that varies considerably between strains or individuals.

Hypocotyl
(Gr. hypo, under + kotyledon, a cup-shape hollow) Portion of an embryo or seedling below the cotyledons, which is a transitional area between stem and root.

Hybridoma
A hybrid cell, derived from a B (antibody producing) lymphocyte fused to a tumour cell, which grows indefinitely in tissue culture and is selected for the secretion of the specific antibody produced by that B cell.

Hypolimnion

The lower layer of a lake.

Hypomorph
A mutation that reduces but does not completely abolish gene expression.

Hypoplastic
Reduction in plant growth or development (dwarfing, stunting) resulting from an abnormal condition associated with a disease or nutritional stress.

Hyperploid
A genetic condition in which a chromosome or a segment of a chromosome is over represented in the genotype. Opposite: hypoploid.

Hypersensitive sites
Regions in the DNA that are highly susceptible to digestion with endonucleases.

Hypertonic
A solution with an osmotic potential greater than that of living cells, leading to water loss from, shrinkage or Plasmolysis of cells in a hypertonic situation. Opposite: hypotonic.

 

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