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  Home >> Molecular Biology Dictionary >> Hemizygous Haplozygous - Heterologous Probe

Hemizygous; haplozygous
The condtion in which only one allele of a pair is present, as in sex linkage or as a result of deletion. Genes present only once in the genotype and not in pairs; as in haploids, in differential, segments of sex chromosomes, or in diploids as a result aeuploidy or loss of chromosome segments.

Heterokaryon
Cell with two or more different nuclei as a result of cell fusion. Opposite homokaryon.

Heterologous
From a different source, as in heterologous DNA.

Heterologous probe
A DNA probe that is derived from one species and used to screen for a similar DNA sequence from another species.

Heredity
Resemblance among individuals related by descent; transmission of traits from parents to offspring.

Heritability
In the narrow sense: 1. the proportion of phenotypic superiority of parent hat is seen in their offspring; 2. the proportion of the total phenotypic variation due to variation in breeding values. In the broad sense: the proportion of the total phenotypic variation due to genetic variation. The degree to which a given trait is controlled by inheritance. See broad-sense heritability; narrow-sense heritability.

Hermaphrodite
1. Animal that has both male and female reproductive organs, or a mixture of male and female attributes. 2. A plant whose flowers contain both stamen and carpels.

Heteroalleles
Mutations that are functionally allelic but structurally non allelic; mutations at different sites in a gene.

HEPA filter
(high .efficiency particulate air filter) A filter capable of screening out particles larger than 0.3 mm. HEPA filters are used in 1. laminar air flow cabinets (hoods) for sterile transfer work. See prefilter.

Heterochromatin
Regions of chromosomes that stain darkly even during interphase, thought to be for the most part genetically inactive. cf euchromatin.

Heteroduplex
A double-stranded DNA molecule or DNA RNA hybrid, where each strand is of a different origin, and consequently containing one or more mismatched (non-complementary) base pairs. A DNA duplex is prepared by the hybridization of single stranded DNA molecules derived from two different sources. Where the two DNAs have identical or very similar sequences, a double stranded molecule will be established, whereas where the two DNAs differ in sequence, single stranded regions will remain. A heteroduplex will be revealed as single strand "bushes" when DNA is observed electron microscopically. A map of homologous and non homologous regions of the two molecules may thereby be constructed. This process is known as heteroduplex mapping.

Heterogametic sex
Producing unlike gametes with regard to the sex chromosomes. In mammals, the XY male is heterogametic, and the XY female is homogametic.

Heterogeneity
See genetic heterogeneity.

Heterogeneous nuclear RNA (hnRNA)
Large RNA molecules, which are unedited mRNA transcripts, or pre mRNAs found in the nucleous of a eukaryotic cell. See RNA.

 

 

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