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  Home >> Molecular Biology Dictionary >> Dimorphism - Disease

Dimorphism
The existence of two distinctly types of individuals within a spcies. An obvious example is the sexual dimorphism in certain animals.

Diplochromosome
See endorduplication.

Diploid
(Gr. diploos, double + oxide, like) 1. The status of having two complete sets of chromosomes, most commonly one set of paternal origin and the other of maternal origin 2. An organism or cell with a double set (2n) of chromosomes (most commonly one of paternal origin, and the other of maternal origin), or referring to an individual containing a double set of chromosomes per cell. Somatic tissues of higher plants and animals are ordinarily diploid in chromosome constitution, in contrast with the haploid gametes.

Diploid cell
A cell which contains two sets of chromosomes. cf haploid cell.

Diplonema
(adj: diplotene) Stage in prophase of meiosis I following the Pachytene stage, but preceding diakinesis, in which one pair of sister chromatids begin to separate from the other pair, i.e., the centromeres beign to disjoin.

Diplophase
Phase with 2n chromosomes.

Dipole (electric)
A pair of equal yet opposite electrical charges that are separated by a small distance.

Direct embryogenesis
Embryoids form directly in culture, without an intervening callus phase, on the surface of zygotic or somatic embryos or on explant tissues (leaf section, root tip, etc).

Direct organogenesis
Formation of organs directly on the surface of cultured intact explants. The process does not involve callus formation.

Direct repeat
Two or more stretches of DNA within a single molecule which have the same nucleotide sequence in the same orientation. Direct repeats may be either adjacent to one another or far apart on the same molecule. For example TATTA...TATTA ATAAT...ATAAT.

Directed mutagenesis
The process of generation of nucleotide changes in cloned genes by anyone of several procedures, including site-specific and random mutagenesis. Also called in vitro mutagenesis.

Directional cloning
The technique by which DNA insert and vector molecules are digested with two different restriction enzymes to create non-­complementary sticky ends at either end of each restriction fragment, so allowing the insert to be ligated to the vector in a. specific orientation and preventing the vector from re-circularizing. See cloning.

Disarm

To delete from a plasmid or virus genes that are cytotoxic or tumour inducing.

Discontinuous variation
Phenotypic variation involving distinct classes, such as red versus white, tall versus dwarf. See continuous variation.

Discordant
Members of a pair showing different, rather. than similar, characteristics.

Disease
(L. dis, a prefix signifying the opposite + M.E. aise, comfort) The opposite of ease. Any alteration from the state of metabolism necessary for the normal development and functioning of an organism, usually associated with infection by a pathogen or the malfunction or absence of one or more genes.
Any impairment of the normal function of an organism.

 

 

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