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  Home >> Molecular Biology Dictionary >> Comparative Positional Candidate Gene - Genetic Complementation

Comparative positional candidate gene
A gene that is likely to be located in the same region as a DNA marker that has been shown to be linked to a single-locus trait or to a quantitative trait locus (QTL), where the gene's likely location in the genome of the species in question is based on its known location in the map of another species, i.e., is based on the comparative map between the two species.

Competence
Ability of a bacterial cell to take up DNA molecules and become genetically transformed.

Competency
An ephemeral state, induced by treatment with cold cations, during which bacterial cells are capable of taking up foreign DNA.

Competent
A competent cell is capable of developing into a fully functional embryo. The opposite is non-competent.

Complement proteins
Proteins that bind to antibody-antigen complexes and help degrade the complexes by proteolysis.

Complementarity
The relationship between the two strands of a double helix of DNA. Thymine in one strand pairs with adenine in the other strand, and cytosine in one strand pairs with guanine in the other strand

Complementarity-determining regions
See CDR.

Complementary DNA
See cDNA.

Complementary entity
1. One of a pair of nucleotide bases that form hydrogen bonds with each other. Adenine (A) pairs with thymine (T) [or with Uracil (U) in RNA], and guanine (G) pairs with cytosine (C). 2. One of a pair of segments or strands of nucleic acid that will hydridize (join by hydrogen bonding) with each other. complementary genes Two or more interdependent genes, such that (in the case of dominant complementarity) the dominant allele from either gene can only produce an effect on the phenotype of an organism if the dominant allele from the other gene is also present; or (in the case of recessive complementarity) only double homozygous recessive show the effect.

Complementary homopolymeric tailing
The process of adding complementary nucleotide extensions to different DNA molecules, e.g., dG (deoxyguanosine) to the 3' -hydroxyl ends of one DNA molecule and dC (deoxycytidine) to the 3 '-hydroxyl ends of another DNA molecule to facilitate, after mixing, the joining of the two DNA molecules by base pairing between the complementary extensions. Also called dG - dC tailing, dA - dT tailing.

Complementary nucleotides
Members of the pairs adenine-thymine, adenine-uracil, and guanine-cytosine that have the ability to hydrogen bond to one another. See nucleotide.

Complementation
See genetic complementation.

 

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