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  Home >> Molecular Biology Dictionary >> Attatched growth reactor - Autologous

Attached growth reactor
A reactor in which the microorganisms are engineered surfaces within the reactor. Examples growth reactors are the trickling filter and the rotating biological contactor. See suspended growth reactor.

ATG or AUG

The codon for methionine; the translation initiation codon.  Usually, protein translation can only start at a methionine coden (although this codon may be found elsewhere within the  protein sequence as well). In eukaryotic DNAis ATG; in RNA it is AUG. Usually, the first mRNA is the point at which translation starts,  and an open reading frame  follows - i.e. the nucleotides taken three at a time will code for the amino acids of the protein, and a stop  codon will be found only when the protein coding region is  complete.

ATP
(adenosine triphosphate) A nucleotide of fundamental importance as a carrier of chemical energy organisms. It consists of adenosine with three phosphate groups; linked together linearly. The phosphate  are attached to adenosine through its ribose (sugar) portion.

Upon hydrolysis, bonds yield either one  molecule of ADP (adenosine diphosphate) and an inorganic phosphate, or on AMP (adenosine monophosphate)and pyrophosphate and pyrophosphate; in both  cases releasing energy that is used to power biological processes. ATP is regenerated by rephosphorilation of AMP and ADP, using chemical energy derived from the oxidation of food.

ATP-ase
An enzyme that brings about the hydrolysis of ATP, by the cleavage of either one phosphate group with the ADP and inorganic phosphate, or of two phosphate groups with the formation of AMP and pyrophosphate.

Attenuated vaccine
A virulent organism that has been modified to produce a less  virulent form, but nevertheless retains ability to elicit antibodies the against the virulent form.
Attenuation

A mechanism for controlling gene expression in prokaryote that involves premature termination of transcription.

Attenuator
A nucleotide sequence in the 5' region of a prokaryotic gene (or in its RNA) that causes premature termination of transcription, possibly by forming a secondary structure.

s

Austenite
face-centered cubic iron; also iron and steel alloys that hay the FCC structure.

Authentic protein
A recombinant protein that has all the properties - including any post-translational modifications - of its naturally occurring counterpart.

utocatalytic reaction
See autocatalysis.

Auto-immune disease

Disorder in which the immune systems of affected individuals produce antibodies against molecules that are normally produced by those individuals (called self antigens).

Auto-immunity
A disorder in. the body's defence mechanism in which immune response is elicited against its own (self) tissues.

Autologous cells

Cells that are taken from an individual, cultures (or stored), and Possibly, genetically manipulated before being infused back into the original donor.

 

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