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  Home >> Molecular Biology Dictionary >> Anthihaemophilic globulin - Ap 1site

Antihaemophilic globulin
Blood globulin that reduces the clotting time of hemophilic blood.

Anti-idiotype antibodies

Antibodies which recognize the binding site of other antibodies. Their binding sites are complement to the binding sites of another immunoglobulin. When animal becomes immune to something, it not only acquires antibodies against that something, it also acquires antibodies against those antibodies. This forms a network of antibodies which can all bind to each other to various degrees, helping t regulate the immune response. Some allergic responses are' part due to the breakdown of this sort of regulation.


Antinutrients

Compounds that inhibit normal uptake of nutrient

Anti-oncogene

A gene whose product prevents the normal growth of tissue. cf recessive oncogene.

Antioxidant

Compound that slows the rate of oxidation reaction.

Antiparallel orientation
The normal arrangement of the two strands of a DNA molecule, and of other nucleic-acid duplexes (DNA-RNA, RNA A), in which the two strands are oriented in opposite directions so that the 5'-phosphate end of one strand is aligned with the 3'-hydroxyl end of the complementary strand.

Antisense DNA

1. The strand of chromosomal DNA that is transcribed

2. A DNA sequence that is complementary to all or an mRNA molecule.

Antisense gene
A gene that produces a transcript (mRNA) that is complementary to the pre-mRNA or RNA of a normal gene (usually constructed by inverting the coding region relative to the promoter).

Antisense RNA

An RNA sequence that is complementary to all or part of a functional mRNA .molecule, to which it binds, blocking its translation. See RNA .

Antiseptic

Any substance that kills or inhibits the growth of disease-­causing micro-organism (a micro-organism capable of causing sepsis), but is essentially non-toxic to cells of the body.

Antiserum
The fluid portion of the blood of an animal (after coagulation of the blood), containing antibodies.

Anti-terminator

A type of protein which enables RNA polymerase to ignore certain transcriptional stop or termination signals and read through them to produce longer mRNA transcripts.

Antitranspirant
A compound designed to reduce transpiration when sprayed or painted on leaves of newly transplanted trees, shrubs or vines, or used as a dip for cuttings in lieu of misting; may interfere with photosynthesis and respiration if the coating is too thick or unbroken.

AP-I site
The binding site on DNA at which the transcription "factor" AP-I binds, thereby altering the rate of transcription for the adjacent gene. AP-I is actually a complex between c-fos protein and c-jun protein, or sometimes is just c-jun dimers. The AP­I site consensus sequence is (C/G)TGACT(C/ A)A. Also known as the TPA-response element (TRE). [TPA is a phorbol ester, tetradecanoyl phorbol acetate, which is a chemical tumor promoter].

 

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