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  Home >> Molecular Biology Dictionary >>Alkylting - Agents Allopatric Specification

Alkylating agents
Chemicals that transfer alkyl (methyl, ethyl, etc.) groups to the bases in DNA.

Allele
(Gr. allelon, of one another, mutually each other); allelomorph e (adj: allelic, allelomorphic). One of a pair, or series of variant forms of a gene that occur at a given locus in a chromosome. Alleles are symbolized with the same basic symbol (e.g., B for dominated and b for recessive); B1, B2, …, Bn for n additive alleles at a locus). In a normal diploid cell there are two alleles of any one gene (one from each parent), which occupy the same relative position (locus) on homologous chromosomes.  Within a population there may be more than two alleles of a gene. See multiple alleles.

Allele frequency
The number of copies of an allele in a population, expressed as a proportion of the total number of copies of all alleles at a locus in a population.

Allele-specific amplification (ASA)

The use of polymerases chain reaction (PCR) at a sufficiently high stringency that only a primer with exactly the same sequence as the target DNA will be amplifies. A powerful means of genotyping for single-locus disorders that have been characterized at the molecular level.

Allelic exclusion

A phenomenon whereby only one functional allele of an antibody gene can be assembled in given B lymphocyte in a diploid mammalian cell cannot undergo a functional re-arrangement, which would result in the production of two different antibodies by a single plasma cell.

Allelomorph
See allele.

Allelopathy
The phenomenon by which the secretion of chemical, such as Phenolic and terpenoid compounds, by a plant inhabits the growth or reproduction of other plant species with which it is competing.

Allergen

An antigen that provokes an immune response.

Allogamy
Cross fertilization in plants. See fertilization

Allometric
When the growth rate of one part of an organism differs from that of another part or of the rest of the body.

Allopatric specication
Speciation occuring at least in part because of geographic isolation.

 

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