Syphilis
Syphilis (Gr. syn = together; philein = to love) is a contagious sexually transmitted disease caused by a spirochete, namely, Treponema pallidum which is about 10-5
m in length and about 0.15
m in diameter.
The pathogen enters the body through mucous membranes or minor breaks or abrasions of the skin. Once in the body, it migrates to the regional lymph nodes and rapidly spreads throughout the body. Syphilis occurs in three distinct stages. In primary stage, the pathogen multiples developing a characteristic lesion called chancre formed within 3-6 weeks. The secondary stage begins 6 to 8 weeks after appearance of the lesion. During this stage these is appearance of cutaneous lesions involving mucus membrane such as on lips, tongue, throat, penis, angina and other body surfaces. In addition, patient suffers from headache, low-grade fever, and enlargement of lymph nodes.


