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Home >> Microbiology >> Industrial Microbiology >> Industrial Microbiology Introduction

Industrial Microbiology
Use of microorganisms, usually grown on a large scale, to obtain valuable commercial products by way of significant chemical transformations is called industrial microbiology. This discipline of microbiology dates back and originated with beat and wine making fermentation processes (alcoholic fermentation) and subsequently expanded in the area of production of pharmaceuticals (e.g., antibiotics), food additives (e.g., amino acids), organic acids (e.g., butyric acid and citric acid), enzymes (e.g., amylases, proteases), and virtamins. All these products are obtained by enhancing the metabolic reactions that microorganism were already capable of carrying out in natural conditions. But, at present, in addition to this traditional industrial microbiology, a new era of microbial biotechnology is fastly expanding in which the genes of the microorganisms responsible for such and other metabolic reactions are being manipulated to give to many new products at commercial level .

The major microorganisms used to carry out important chemical transformation (biocatalytic processes) are the microfungi (yeasts and moulds) and certain prokaryotes (e.g., Streptomyces). The ultimate source of all strains of microorganisms used in biocatalytic processes is nature. Actually, all such microbial strains are normally far-removed from the “wild-type” condition that existed when the strain was first isolated. Once the valuable industrial microorganism comes to hand, it is concerned by both microbiology laboratory in industry as well as in microbial culture collection centres of atleast national-recognition level.
A microorganism suitable of r industrial use must :
(i) be capable of growth and product formation in large-scale culture.

(ii) produce spores or some other units of propagation so that is can be easily inoculated into large fermenters.

(iii) grow rapidly and produce the desired product in a relatively short period of time.

(iv) be able to grow in a relatively inexpensive nutrient medium (culture medium) obtainable in bulk quantities.

(v) not be pathogenic, especially to humans or economically animals or plants, and

(vi) be amenable to genetic manipulation so that its genetic material can be easily altered to obtain increased yields.

Microbial products of industrial interest are of several major types including the microbial cells themselves (yeasts cultivated for food, baking or brewing; production of single cell protein, etc.) and substances produced by the microbial cells). This chapter covers, however, the brief accounts of the microbial production of organic acid, amino acids, enzyme, alcohols, alcohols, other alcoholic beverages, antibiotics, food supplement products and vitamins.

 

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