Status of the Production of Different Antibiotics in India,Penicillin,Ampicillin,Amoxillin,Cloxacillin,Streptomycin,Chloramphenicol,Tetracyclin

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Home >> Industrial and Microbial Biotechnology >> Microbes and Microbial Genomics for Industry >> Status of the Production of Different Antibiotics in India

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Status of the production of different antibiotics in India (based on data from DGTD, 1989).

Quantities (annual)				Production units in India
	Capacity (1989-90)	Production (1985)	Import (or excess demand)	Production units in India
1. Penicillin Ampicillin	637 MMU 150 tonnes	481 MMU 110 tonnes	-- 600 MMU	HAL, IDPL, Allembic Chemicals
Amoxicillin	37 tonnes	1.4 tonnes	470 tonnes	--
Cloxacillin	Total demand In 1990, 21 tonnes		35.6 tonnes	--
Cephaloxin	10 tonnes	3 tonnes	37 tonnes	Standard Pharmaceuticals
2. Streptomycin	445 tonnes	200 tonnes	70 tonnes	IDPL, HAL, Symbiotics
3. Chloramphenicol	185 tonnes	86 tonnes	214 tonnes	--
4. Tetracyclin	220 tonnes	219 tonnes		IDPL
5. Erythromycin	88 tonnes	30 tonnes	60 tonnes	Alembic
6. Gentamycin	1.0 tonnes	437 kg	2.5 tonnes	HAL
7. Rifampicin and neomycin	140 tonnes	No production	100 tonnes + 16 tonnes	--
8. Kanamycin	1000 kg	No production	17 tonnes	Alembic

Penicillin is used to produce semi-synthetic penicillin - 6 APA (ampicillin, amoxicillin and cloxacillin) and 7ACDA (cephaloxin). The use of 6APA and 7ACDA has increased due to their lower side effects; they are manufactured from Penicillin G.
HAL = Hinidustan Antibiotics Ltd. Pune
IDPL = India Drugs & Pharmaceuticals Ltd., Rishikesh

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