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Home >> Industrial and Microbial Biotechnology >> Microbes and Microbial Genomics for Industry >> Microbes used for Production fo Antibiotics

Microbes used for production of antibodies
Fungi, bacteria and actinomycetes are important antibiotic producing organisms. Most species of Streptomyces are quite active in the production of a variety of antibiotics. Some microorganisms, and the antibiotics produced by them are listed in the table.

Some micro-organisms and antibiotics produced by them

Organism

Antibiotic

Penicillium spp.

Penicillin

Bacillus licheniformis

Bacitracin

Cephalosporium acremonium

Cephalosporin

Nocordia uniformis

Norcardins

S. caespitosus

Actinomycins

Streptomyces antibiotics

Mitomycin

S. erythreus

Erythromycin

S. griseus

Streotomycin, Cycloheximide

S. virginae

Virginiamycin


The most important aspect of microbial antibiotic production is the selection of high yielding strain and a suitable fermentation medium. Since antibiotics are the secondary metabolities of an organism, it is necessary to limit the growth of the micro-organisms and to divert the organism from primary to secondary metabolism. This is usually achieved by designing the medium in such a way that a key nutrient is exhausted at appropriate time, producing the desired metabolic switch or diversion.

 

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