Creating new products and new reactants
Biosynthetic genes for secondary metabolites can also be transferred and expressed in a heterologous host, enabling it to produce novel products or reactants such as follows: (i) Recombinant Streptomyces strains could be produced for production of antibiotics like mederrhodins A and B, dihydrogranatirhodin, 2-norerythromy­dn A, B, C and D, and   isovaleryl spiramycin, (ii) New reactants may be produced in the form of new compounds. These include transfer to E. coli, of naphthalene dioxygenase gene (for the synthesis of indigo) from Pseudomonas putida, tyrosinase gene (for the synthesis of melanin) from Streptomyces antibioticus and toluene mono-oxygenase gene (for degradation of trichlorethylene, a widespread pollutant) from P. mendocina.