‘Genomics’ Drugs (Pharmacogenomics)
Drug discovery in the 21st century will also have to respond to the concept of pharmacogenimcs, which requires that for the same disease different drugs need to be prescribed, keeping in view the patient’s response to individual drugs. This aspect was discussed in some detail. This area of drug development will also be facilitated by e-cell simulation of causal and temporal behaviour of the cell as a network of genes and genes products. Such an ‘e-cell’ project is being used in Japan. Which reports simulation of a set of metabolic pathways in a cell that takes up glucose and excretes lactase. This area of research and its use in drug discovery will expand in future. Although ‘genomics’ drugs may take time to come to the markets, prognostic genotyping and diagnostic molecular profiling will certainly be used in routine medical practice in not too distant a future
Impact of Genomics and Computational technologies on pharmaceutical R & D and personalized patient health care



