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Home >> Genetics >>Gene and Gene Concept

Gene and Gene Concept

Gene is the fundamental unit of hereditary. Its presence was first proposed by Mendel in 1865. He called it as factor. The word ‘gene’ was coined by Johannson in 1909. A gene is defined as a segment of DNA having a particular sequence of nucleotides coding for a specific polypeptide chain. It occupies a define locus in the chromosome and it is responsible for the expression of a specific character; it is an unit of mutation.

Size of a Gene
An average gene consists of 1500 nucleotide base pairs and has a molecular weight of 10.6. The haemoglobin has two types of polypeptide chains, namely alpha and beta chains. The alpha chain is synthesized by a gene containing 423 nucleotides (141 ´ 3= 423) and the beta chain is synthesized by a gene containing 438 nucleotides (146 ´ 3 = 438).

Cistron
It is a modern term for gene. This term was coined by Benzer. Cistron is a portion of DNA specifying a single polypeptide chain.
Muton
It is the smallest length of DNA capable of mutation. This term is coined by Benzer. A muton consists ofa single nucleotide or many nucleotides.
Recon
A recon is the smallest unit of DNA capable of recombination.

 

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