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  Home >> Genetics Dictionary >> tRNA Transfer RNA Transition

Transfection
The introduction of foreign DNA into a host cell.

Transfer RNA (tRNA)


A class of RNA having structures with triplet nucleotide sequences that are complementary to the triplet nucleotide coding sequences of mRNA.

The role of tRNAs in protein synthesis is to bond with amino acids and transfer them to the ribosomes, where proteins are assembled according to the genetic code carried by mRNA.
Small RNA molecules that act as adaptor molecules during protein synthesis. Each tRNA molecule contains a specific three-base segment called an anticodon, which binds to the complementary codon in m RNA, and a binding site for a specific amino acid.

3. A type of RNA that brings the amino acids to the ribosomes to make proteins. There are 20 kinds of transfer RNA molecules, one for each of the 20 main amino acids.

A transfer RNA molecule has an amino acid attached to it, and contains the anticodon corresponding to that amino acid in another part of its structure. In protein synthesis, each codon in the messenger RNA combines with the appropriate tRNA’s anticodon, and the amino acids are arranged in order to make the protein.

Transformation
A process by which the genetic materials carried by an individual cell is altered by incorporation of exogenous DNA into its genome.
2. The phenomenon by which genes are transmitted from one bacterial strain to another in the form of soluble fragments of DNA that may originate form live or dead cells; one inside, a fragment usually replaces, by recombination, a short section of the DNA of the receptor cell that contains a zone of homology.

Transformation (bacteria)
Genetic alteration of bacteria as a result of uptake of foreign DNA by the bacteria.

Transformism

The evolutionary theory of Lamarck in which changes occur within a lineage of populations, but in which lineages do not split (i.e., no speciation occurs, at least not in the sense of the cladistic species concept) and do not go extinct.

Transgenic

An experimentally produced organism in which DNA ahs been artificially introduced and incorporated into the organism’s germ line.
2. A term applied to organisms that have been genetically modified to incorporate foreign DNA into their genomes.

Translation
The process in which the genetic code carried by mRNA directs the synthesis of proteins from amino acids.
2. The creation of a protein derived from messenger RNA.
3. The formation of a protein directed by a specific messenger RNA molecule.

Translocation

A mutation in which a large segment of one chromosome breaks off and attaches to another chromosome.
2. The transfer of one segment of one chromosome to another chromosome (ie reciprocal and Robertsonian).
3. A chromosome rearrangement in which the chromosomes are not arranged in the typical set of 23 pairs. Even if the correct amount of genetic material is present, an individual with a chromosome translocation is at increased risk for having problems such as difficulty conceiving or maintaining a pregnancy. Chromosome translocations are often inherited.
4. A chromosome aberration which results in a change in position of a chromosomal segment within the genome, but does not change the total number of genes present.

Transition

A mutation changing one purine into the other purine, or one pyrimidine into the other pyrimidine (i.e., changes from A to G, or vice versa, and changes from C to T, or vice versa).

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