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  Home >> Genetics Dictionary >> Primer - Prophase

Primer
Short preexisting polynucleotide chain to which new deoxyribonucleotides can be added by DNA polymerase. 2. A short length of RNA or single-stranded DNA that is necessary for the initiation of DNA synthesis.

Privacy
In genetics, the light of people to restrict access to their genetic information.

Probe
Single-stranded DNA or RNA molecules of specific base sequence, labeled either radioactively or immunologically, that are used to detect the complementary base sequence by  hybridization.

Probability
The long-term frequency of an event relative to all alternative events and usually expressed as a decimal fraction.

Proband
The family member through whom the family history is ascertained.

Pronucleus
The nucleus of a sperm or egg prior to fertilization. See also: nucleus, transgenic.

Proofreading
A molecular mechanism for detecting and correcting errors in replication.

Product Law
A law that states that the probability of two independent events occurring simultaneously is equal to the product of the probabilities of each event occurring alone.

Product rule
The rule that states that the probability of the occurrence of independent events is the product of their separate probabilities.

Progeny
The offspring of a mating.

Prognosis
A forecast of the probable course and outcome of an attack of disease and the prospects of recovery as indicated by the nature of the disease and symptoms of the individual.

PROM
Premature rupture of membranes. A term used to describe the amnion and chorion (bag of waters around the baby) rupturing prior to 40 weeks of pregnancy.

Promoter
A DNA site to which RNA polymerase will bind and initiate transcription. 2. A DNA sequence having a regulatory function over the transcription of an adjacent gene, and to which RNA polymerase binds prior to transcription. 3, A region on a DNA molecule to which an RNA polymerase binds and initiates transcription.

Prokaryote
Cell or organism lacking a membrane-bound, structurally discrete nucleus and other subcellular compartments. Bacteria are examples of prokaryotes. 2. Organisms that lack true nuclei, such as bacteria and cyanobacteria. 3. A cell without a distinct nucleus. Bacteria and some other simple organisms are prokaryotic. Compare with eukaryote. In classificatory terms, the group of all prokaryotes is paraphyletic. 4. Microorganisms that lack a membrane-bound nucleus containing chromosomes; other organelles are also absent.

Prophase
The first stage of cell division (meiotic or mitotic). During this stage, chromosomes begin to condense, the nuclear envelope breaks down, and centrioles replicate. In meiosis, the first prophase is divided into five substages: leptonema, zygonema, pachynema, and diakinesis.

 

 

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