students Logo
Home | Sitemap | Contact us | Search | Language
  CareerCareers Exams Competitive Exams College Colleges Scholarship Scholarships Loan Loans Results Exam Results Login Login
Left Right
  Home >> Genetics Dictionary >> Ligand - Linnaean Classification

Library
An unordered collection of clones (i.e, cloned DNA from a particular organism ) whose relationship to each other can be established by physical mapping. See also: genomic library, arrayed library.

Ligand
A molecule that binds to a receptor.

Ligase
An enzyme that catalyzes the formation of a phosphodiester bond between adjacent 3'-OH and S'-P atoms in DNA.

Ligation
The joining of DNA molecules by the enzyme DNA ligase.

Lineage
An ancestor -  descendant sequence of (1) populations, (2) cells, or (3) genes.
Linkage
The proximity of two or more markers (e.g., genes, RFLP markers) on a chromosome; the closer the markers, the lower the probability that they will be separated during DNA repair or replication processes (binary fission in prokaryotes, mitosis or meiosis in eukaryotes), and hence the greater the probability that they will be inherited together.
2. The occurrence of different genes on the same chromosome that are usually inherited together.

3. A condition in which two non-allelic genes tend to be inherited together. Linked genes are found on the same chromosome and do not assort independently, but can be separated by crossing over.
4. The greater association in inheritance of two or more nonallelic genes than is to be expected from independent assortment; genes are linked because they reside on the same chromosome.

Linkage disequilibrium
A condition in which the haplotype frequencies in a population deviate from the values they would have if the genes at each locus were combined at random. (When no deviation exists, the population is said to be in linkage equilibrium).
2. Where alleles occur together more often than can be accounted for by chance. Indicates that the two alleles are physically close on the DNA strand. See also: Mendelian inheritance.

3. Greater co-occurrence of two genetic markers( on the same chromosome, as a haplotype) ion a population than would be expected for independent markers. Usually, LD is generated when the markers are located close together on the same chromosome. When variants of two genetic loci are in string LD, the variant seen on locus are predictive of the variant found at the other on an individual chromosome.

Linkage group
A group of genes that have their loci on the same chromosome.

Linkage map
A map of the relative positions of genetic loci on a chromosome, determined on the basis of how often the loci are inherited together. Distance is measured in centimorgans(cM)

Linked
Of genes, present on the same chromosome

LinkedGenes (Linked Markers)
Genes and / or markers that are closely associated on a chromosome. This determination is usually by means of linkage analysis, but may also be inferred if the markers are in linkage disequilibrium.

Linnaean classification
A hierarchical method of naming classificatory groups, invented by the eighteenth century Swedish naturalist Carl von Linne, or Linnaeus. Each individual is assigned to a species, genus, family, order, class, phylum, and kingdom, and some intermediate classificatory levels. Species are referred to by a Linnaean binomial of its genus and species, such as Magnolia grand flora.

 

Left Right