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  Home >> Genetics Dictionary >>Leakey Richard - Levine Michael

Leakey, Richard
The son of renowned anthropologists Louis and Mary Leakey, Richard continued their work an early hominids from 1964 until the 1980s, making a number of significant fossil finds in the Lake Turkana area and serving as Director of the National Museum of Kenya. Later the devoted his energies to conservation and politics.

Levine, Michael

Professor of Genetics and Development in the Molecular and Cell Biology Department at University of  California, Berkeley. Discoverer (with Bill McGinnis) of homeobox sequences in the homeotic genes Antennapedia and Ultrabithorax while a postdoctoral researcher with Walter Gehring at the University of Basel, Switzerland.

His current research involves analysis of gene regulation and patterning in the early Drosophila embryo; studies of embryonic development in the tunicate, Ciona intestinalis, focused on the specification of the notochord and tail muscles; and a critical test of classical models for the evolutionary origins of the chordate body plan.
Lee, Melanie
A molecular geneticist and microbial biologist, who in the 1980s collaborated with Paul Nurse on novel research that demonstrated the commonality of the genetic code between yeasts and humans. Dr Lee later took her molecular skills into the pharmaceutical industry, and was a leader in moving pharmacology away from animal models and towards the use of recombinant DNA technology for screening potential new therapies. She now heads the research division of Celltech, an international  biopharmaceutical company, where her team works on drug discovery and development of new therapies, mainly for the treatment of inflammatory and immune diseases.

Lek
An area of ground divided into territories that are defended by males for the purpose of displaying to potential mates during the breeding season. This form of mating behaviour is known as lekking, and occurs in various bird species (for example the peacock) and also in some mammals. The dominant males occupy the territories at the centre of the lek, where they are most likely to attract and mate with visiting females. The outer territories are occupied by subordinate, males who have less mating success.

Over successive breeding seasons, younger subordinate males tend to gradually displace older individuals from most desirable territories and become dominant themselves. The lek territories do not contain resources of value to the female; such as food or nesting materials, although males of some species may build structures such as bowers that form part of their display.

Lemur
A small, tree-dwelling primate that belongs to the group called prosimians.

Leptonema (adjective: leptotene)
The stage of meiotic prophase I that precedes synapsis. Chromosomes are not yet fully condensed, and are seeking their homologues.

Lethal mutation
A mutation that renders the organism or cell possessing it inviable.

Lethal recessive
The case in which inheriting two recessive alleles of a gene causes the death of the organism.

Leucine zipper
A structural motif found in members of one family of transcription factor, characterized by leucine residues occurring in the polypeptide every seventh amino acid. Leucine zippers - ­on two polypeptides appear to interact to form a dimer that binds to DNA.

 

 

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