Imprinting
A phenomenon in which the disease phenotype depends on which parent passed on the disease gene. For instance, both Prader –Willi and Angelman syndromes are inherited when the same part of chromosome 15 is missing. When the father’s complement 15 is missing, the child has Prader-Willi, but when the mother’s complement of 15 is missing, the child has Angleman syndrome.

2. A biochemical phenomenon that determines, for certain genes, which one of the pair of allele, the mother’s or the father’s will be active in that individual.

Inbreeding
Mating between two closely related organisms. The crossing of closely related plants or animals

Independent assortment
During meiosis each of the two copies of a gene is distributed to the germ cells independently of the distribution of other genes.
2. The random distribution of chromosomes to gametes during meiosis. The distribution of one pair alleles is independent of other genes on non-homologous chromosomes.

Index Repository
Our collection of immortalized cell lines established from unrelated individuals and members of extended families. The individuals were chosen to represent a large proportion of human diversity, facilitate the quality control analysis of the polymorphic discovery process and enable the electronic discovery of HAPTM Markers.

Inducer
An effector molecule (such as lactose in the lac  operon) that activates transcription.