students Logo
Home | Sitemap | Contact us | Search | Language
  CareerCareers Exams Competitive Exams College Colleges Scholarship Scholarships Loan Loans Results Exam Results Login Login
Left Right
  Home >> Genetics Dictionary >> Backcross - Base sequence

Back cross
A cross between an animal that is heterozygous for alleles obtained from two parental strains and a second animal from one of those parental strains. Also used to describe the breeding protocol of an outcross followed by a backcross.
2. A cross between an F1 heterozygote and an individual with the parental genotype.

Background Risk
The empirically derived risk of a given condition or event in the population as a whole.

Base sequence
The order of nucleotide bases in a DNA molecule; determines structure of proteins encoded by that DNA.

Base Analogue
Unnatural purine or pyrimidine nucleotide differing slightly from normal bases that can be incorporated into DNA, often causing a mutation.

Bacteria
Tiny, single-celled, prokaryotic organisms that can survive in a wide variety of environments. Some cause serious infectious diseases in humans, other animals, and plants.

Bacterial Artificial Chromosome (BAC)
A vector used to clone DNA fragments (100-to 300-kb) insert size; average, 150 kb) in Escherichia coli cells. Based on naturally occurring F-factor plasmid found in the bacterium E.coli.

Base
One of the molecules that form DNA and RNA molecules. See also: nucleotide, base pair, base sequence.
2. The molecular building blocks of DNA and RNA. In DNA, adenine (A), thymine (T), guanine (G), and cytosine (C). In RNA, uracil (U) replaces thymine. In DNA, A bonds with T and C bonds with G. In RNA, A bonds with U and C bonds with G.
3. The DNA molecule is a chain of nucleotide units; each unit consists of a backbone made of a sugar and a phosphate group, with a nitrogenous base attached. The base in a unit is one of adenine (A), guanine (G), cytosine (C), or thymine (T). In RNA, uracil (U) is used instead of thymine. A and G belong to the chemical class called purines; C, T, and U are pyrimidines.

Bacteriophage
A virus that infects bacteria (synonym:phage).

Barr body
A dense mass of chromatin in nuclei of placental mammals, believed to be the inactivated X chromosome.
2. The condensed single X chromosome seen in the nuclei of somatic cells of female mammals.

Base pair (bp)
Two nitrogenous bases (adenine and thymine or guanine and cytosine) held together by weak bonds. Two strands of DNA are held together in the shape of a double helix by the bonds between base pairs.
2. A pair of complementary nucleotide bases, as in double ­stranded DNA. Used as the unit of measurement of the length of a DNA sequence.

 

Left Right