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Home >> Biotechnology and Genomics >> Mass Spectrometry - An Essential Tool for Genome and Proteome Analysis >>Linear TOF-MS

Linear TOF-MS.
In linear spectrometers using MALDI and TOF, samples are deposited on a metal substrate, capable of holding several hundred analyte spots. Irradiation of these spots by a laser pulse generates a short burst of ions, which are accelerated to a fixed amount of kinetic energy in order to travel down a flight tube. The small ions have a higher velocity than the larger ones, thus producing a time of flight (TOF) spectrum.

Schematic Representation of Basic Components of a Liner TOF Mass Spectrometer

Schematic Representation of Basic Components of a linear TOF Mass Spectrometer

 

 

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