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Home >> Biotechnology and Genomics >> Bioinformatics and Data Mining - In Silico Biology >> List of Major Events in Bioinformatics

List of major events in bioinformatics (including those, which occurred before the term bioinformatics was coined)

1962

Pauling’s theory of molecular evolution

1967

Margaret Dayhoff’s Atlas of Protein Sequences

1970

Needleman-Wunsch algorithm

1977

DNA sequencing and software to analyze it (Staden)

1981

Smith-Waterman algorithm developed

1981

The concept of a sequence motif (Doolittle)

1982

GenBank Release 3 made public

1982

Phage lambda genome sequenced

1983

Sequence database searching algorithm (Wilbur-Lipman)

1985

FAST/FASTN: fast sequence similarity searching

1988

National Center for Biotechnology Information (NCBI) created at NIH/NLM

1988

EMBnet network for database distribution

1990

BLAST: fast sequence similarity searching

1991

EST: expressed sequence tag sequencing

1993

Sanger Centre, Hinxton, UK

1994

EBI (European Bioinformatics Institute), Hinxton, UK

1995

First bacterial genomes completely sequenced

1996

Yeast genome completely sequenced

1997

PSI-BLAST

1998

Worm (multicellular) genome (C. elegans) completely sequenced

1999

Fruitfly (D.melanogaster) genome completely sequenced

2000

Thale cress (A. thaliana) genome sequenced

2001

Draft genome sequences of human (H. sapiens)

2002

Draft genome sequences of rice (Oryza sativa)

 

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