List of major events in bioinformatics (including those, which occurred before the term bioinformatics was coined)
| 1962 | Pauling’s theory of molecular evolution |
1967 |
Margaret Dayhoff’s Atlas of Protein Sequences |
1970 |
Needleman-Wunsch algorithm |
1977 |
DNA sequencing and software to analyze it (Staden) |
1981 |
Smith-Waterman algorithm developed |
1981 |
The concept of a sequence motif (Doolittle) |
1982 |
GenBank Release 3 made public |
1982 |
Phage lambda genome sequenced |
1983 |
Sequence database searching algorithm (Wilbur-Lipman) |
1985 |
FAST/FASTN: fast sequence similarity searching |
1988 |
National Center for Biotechnology Information (NCBI) created at NIH/NLM |
1988 |
EMBnet network for database distribution |
1990 |
BLAST: fast sequence similarity searching |
1991 |
EST: expressed sequence tag sequencing |
1993 |
Sanger Centre, Hinxton, UK |
1994 |
EBI (European Bioinformatics Institute), Hinxton, UK |
1995 |
First bacterial genomes completely sequenced |
1996 |
Yeast genome completely sequenced |
1997 |
PSI-BLAST |
1998 |
Worm (multicellular) genome (C. elegans) completely sequenced |
1999 |
Fruitfly (D.melanogaster) genome completely sequenced |
2000 |
Thale cress (A. thaliana) genome sequenced |
2001 |
Draft genome sequences of human (H. sapiens) |
2002 |
Draft genome sequences of rice (Oryza sativa) |


