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Home >> Biotechnology Dictionary >> Homogametic-sex - Hypochlorite

Homogametic sex - producing similar gametes with regard to the sex chromosomes. In mammals, the XY male is heterogametic, and the XX female is homogametic.

Homogenotisation - a genetic technique used to replace one copy of a gene, or other DNA sequence within a genome, with an altered copy of that sequence. The DNA is first cloned and then altered in some way, e.g., a transposon is inserted into a gene. The mutated gene copy can be used to replace the original gene by recombination in vivo. The incorporation of the mutated gene is usually selected, for example, by virtue of its containing a transposon encoded antibiotic resistance.

Homokaryon - cell with two or more identical nuclei as a result of fusion. Opposite: heterokaryon.

Homologous - from the same source, or having the same evolutionary function or structure.

Homologous chromosomes - chromosomes that occur in pairs and are generally similar in size and shape one comes from the male parent and the other from the female. Such chromosomes contain the same linear array of genes.

Homologous recombination - the exchange of DNA fragments between two DNA molecules or chromatids of paired chromosomes (during crossing over) at the site of identical nucleotide sequences.

Homology - the degree of identity between individuals, or characters. The degree of identity between the nucleotide sequences of two nucleic acid molecules or the amino acid sequences of two protein molecules. Although sequence determination is the ultimate test of homology, useful estimates can be provided by either DNA DNA or y: DNA RNA hybridisation.

Homoplasmy - a cellular condition in which all copies of an organelle are genetically identical. See: heteroplasmy.

Homopolymer - a nucleic acid strand that is composed of one kind of nuc1eotide, e.g.,.

Homozygote - (Gr. homos , one and the same. + zygon , yoke) an individual that has two copies of the same allele at a particular locus in its two homologous chromosomes. See allele; genotype; heterozygote.

Hormone - a specific organic product, produced in one part of a plant or animal body, and transported to another part where, at low concentrations, it promotes, inhibits or quantitatively modifies a biological process.

Host - an organism that contains another organism, or a cloning vector.

Host-specific toxin - a metabolite produced by a pathogen which has a host specificity equivalent to that of the pathogen. Such toxins are utilized for in vitro selection experiments to screen for tolerance or resistance to the pathogen.

Humoral immune response - the production of antibody by B cells of the immune system in response to the presence of a foreign antigen. See antibody mediated immune response.

Hybrid selection - the process of choosing individuals possessing desired characteristics from among a hybrid population.

Hybrid vigour - the extent to which the performance of hybrid in one or more traits is better than the average performance of the two parental populations.

Hybridisation - interbreeding of species, races, varieties and so on, among plants or animals; a process of forming a hybrid by cross pollination of plants or by mating animals of different types.

Hybridoma - a hybrid cell, derived from a B (antibody producing) lymphocyte fused to a tumour cell, which grows indefinitely: in tissue culture and is selected for the secretion of the specific antibody produced by that B cell.

Hydrate - a compound formed by the incorporation of water.

Hydrogen bond - a relatively weak bond formed between a hydrogen atom (which is covalently bound to a nitrogen or oxygen atom) and a nitrogen or oxygen atom with an un shared electron pair. Weak interactions between electro negative atoms and hydrogen atoms (electro-positive) that are linked to other electro negative atoms.

Hydrogen uptake positive - a term describing a micro-organism that is capable of assimilating (or taking up) hydrogen gas.

Hydrolysis - a reaction in which a molecule of water is added at the site of cleavage of a molecule to two products.

Hydrophobic - interactions association of non-polar groups with each other when present in aqueous solutions because of their insolubility in water.

Hydroponics - the growing of plants in aerated water containing all the essential mineral nutrients, with no soil. Also called soil less gardening or cultivation.

Hydroxyl end, 3 - The hydroxyl group that is attached to the 3 carbon atom of the sugar (ribose or deoxyribose) of the terminal nucleotide of a nucleic acid molecule.

Hyperploid - a genetic condition in which a chromosome or a segment of a chromosome is over-represented in the genotype. Opposite : hypoploid.

Hyersensitive sites - regions in the DNA that are: highly susceptible to digestion with endonucleases.

Hypertonic - a solution with an osmotic potential greater than that of living cells, leading to water loss from, shrinkage or plasmolysis of cells in a hypertonic situation.

Hypervariable segment - a region of a protein that varies considerably between strains or individuals.

Hypochlorite - generic term for aqueous solutions of sodium hypochlorite, potassium hypochlorite or calcium hypochlorite, which are oxidising agents and used for disinfecting surfaces and surface sterilising tissues, and for bleaching.

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