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Home >> Animal Biotechnology >>Biomedical Application >> Biomedical Applications Introduction

Introduction
The development of treatments, preventive procedures, and cures for human diseases was the outstanding contribution of medicine and science to human well-being in the 20th century. It is difficult to summarize the whole gamut of contributions in a text of limited spaces; these could be grouped under the following broad heads:
1. Disease prevention (vaccines)

2. Disease diagnosis (monoclonal antibodies and probes)

3. Forensic medicine (DNA fingerprinting) Vaccine protects a recipient establishing and immunological resistance to infection.

The effectiveness of vaccines may be appreciated from the fact that smallpox, once a dreaded disease the world over, has been completely, eradicated from the world; the last case of smallpox was reported in 1977.

An accurate diagnosis of the disease and its causal organism is critical to its effective management and cure. Conventionally disease diagnosis is based on the following:

i. Microscopic examination

ii. Culture of specimen

iii. Immunological assays

iv. Detection and measurement of the pathogen-specific antibodies

These tests are often tedious and time-consuming, and may yield ambiguous results and some of them cannot be applied in certain cases. Hence novel diagnostic approaches have been developed by biotechnology, which are precise and very rapid viz. monoclonal antibodies and probes. The knowledge and techniques of medical science applied to assist in the resolutions of crimes, legal disputes, etc. constitute forensic medicine. DNA fingerprinting or DNA profiling is a highly sensitive and extremely versatile approach to solve these problems.

 

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